Crude leaf extracts of Piperaceae species downmodulate inflammatory responses by human monocytes
نویسندگان
چکیده
منابع مشابه
Human major group rhinoviruses downmodulate the accessory function of monocytes by inducing IL-10.
Human rhinoviruses (HRVs) are the predominant cause of the common cold. Although this disease is per se rather harmless, HRV infection is considered to set the stage for more dangerous pathogens in vivo. Here we demonstrate that HRV-14, a member of the major group HRV family, can efficiently inhibit antigen-induced T-cell proliferation and T-cell responses to allogeneic monocytes. HRV-14 trigge...
متن کاملPioglitazone reduces inflammatory responses of human adipocytes to factors secreted by monocytes/macrophages.
Infiltration of monocyte-derived macrophages into adipose tissue may contribute to tissue and systemic inflammation and insulin resistance. We hypothesized that pioglitazone (Pio) could specifically reduce the inflammatory response of adipocytes to factors released by monocytes/macrophages. We show that macrophage factors (Mphi-factors) greatly increase expression levels of proinflammatory adip...
متن کاملTopical anti - inflammatory activity of yacon leaf extracts
Smallanthus sonchifolius (Poepp.) H. Rob., Asteraceae, known as yacon, is an herb that is traditionally used for the treatment of diabetes in folk medicine. However, recent studies have demonstrated that this plant has other interesting properties such as anti-microbial and anti-infl ammatory actions. Thus, the purpose of this study was to evaluate the topical anti-infl ammatory property of dif...
متن کاملAntinociceptive and Anti-inflammatory Activity of Tecoma Stans Leaf Extracts
Tecoma stans (Bignoniaceae) is used in the treatment of diabetes, stomach pains, rheumatism, diuretic, vermifuge and tonic in traditional medicine. The present study has been design to evaluate antinociceptive and anti-inflammatory activities of alcohol and aqueous extracts of Tecoma stans leaves and to determine total phenolic and flavonoid contents. Both extracts shows dose dependent activity...
متن کاملAntioxidant and Anti-Inflammatory Activities of Sasa quelpaertensis Leaf Extracts
Oxidative stress plays a critical role in the pathogenesis of inflammation (Winrow et al., 1993), which is a physiological response that protects the body from stimuli including infections and tissue injury. The magnitude of the inflammatory response is crucial, and insufficient responses result in immunodeficiency, which can lead to infection and cancer. Excessive responses cause morbidity and...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0198682